MCB 2000 Chapter Notes - Chapter 9: Radiography, Frederick Griffith, Frameshift Mutation

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What is genetics: the science of heredity, research in genetics takes place on several levels. Where genetic material can be found: genetic information is contained within genetic material dna and rna, it can be found in, prokaryotic organisms. The size and packaging of genomes: e. coli 4,288 genes, human cell: 20,000 25,000 genes, size of the cell of e. coli 1 mm (diameter, size of the stretched out dna 1mm (1000 times longer) Dna molecule is tightly packed in the form of chromosome. Structure of dna: dna molecule double helix, composed of nucleotides, nucleotides composed of. Bases: purine (adenine, guanine, pyrimidine (cytosine, thymine) Phosphate group: single strands of dna have opposite orientation (3" and 5", g-c held together with 3 hydrogen bonds, a-t held by 2 hydrogen bonds. Topoisomerase unwinds the double helix of dna. Synthesis of the new strand by attachment of complementary nucleotides. Details of replication: helicase opens the double helix, complementary nucleotides attach themselves to the exposed bases.

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