MIC 463 Chapter : Exam 1 Study Guide Virology

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Visual identification section to exam (know slides, identification of virus characteristics by sight, etc) Chapter 1: how do viruses differ from bacteria and eukaryotic cells with respect to size, structure, genomes, culturability, retention by filters, visualization with microscopes, diversity of viral genomes: Family (subfamily), genus, species: baltimore classification system. (major groups based on genome structure, where + strand corresponds to the mrna and strand, the complement of the mrna, basic virion structure. Spherical (icosahedral) vs. helical, naked vs. enveloped (know examples for each: differences in viral attachment in animal, plant, and bacterial cells. Ex: structures used on animal cells or bacterial cell walls for attachment. Role of plasmodesmata in viral infection in plants: steps in viral reproduction: (one step growth experiment, understand how the graph shows these stages and how they relate to each other. Attachment, penetration/uncoating, synthesis (of viral proteins and nucleic acids), maturation (assembly), release: quantifying viral infection: Plaque assay basics (basics of problems we were assigned)

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