BIO 202 Chapter Notes - Chapter 11: Acetylcholine, Supreme Headquarters Allied Powers Europe, Asthma

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Local and long distance signaling: cell junctions - gap junctions - cytoplas(cid:373)"s of t(cid:449)o cells are i(cid:374) co(cid:374)tact (cid:449)ith each other, cell-cell recognition expresses signaling molecule as a transmembrane protein and other cell expresses receptor. Signals and receptors: signal molecule (ligand): fits into receptor such as a lock and key. Bio 202 chapter 11 phemie chan: g protein coupled receptors: a plasma membrane receptor that works with the help of a g protein. Peripheral intracellular membrane proteins; transmembrane signal receptors. Gdp: gtp- lot of energy, gdp no energy does(cid:374)"t (cid:449)a(cid:374)t to do anything. Ligand binding to receptor allows it to change nucleotide there is a mechanism that allows the g protein to exchange. Acts as an on/off switch; bind to gtp (active) when the hydrolyze the bound gtp gdp (deactivated) Once g protein active it is ready to interact and activate other molecules. Bio 202 chapter 11 phemie chan.