PSY 250 Chapter Notes - Chapter 4: Exocytosis, Nitric Oxide, Reuptake

• School: Stony Brook University
• Department: Psychology
• Course: PSY 250
• Professor: Hoi- Chung Leung

Document Summary

Membrane potential = difference in electrical charge b/w inside and outside of cell. Use microelectrodes to measure (one inside neural membrane, one outside) Resting membrane potential ~ -60 to -80 mv: neuron in resting state = polarized, neg to positive ion > inside neuron. Random motion ions in tissue = constant random motion: more likely to move down concentration dradients, promotes even distrib of ions. Electrostatic pressure accum of charges in one area dispersed by repulsion of like charges. 4 important ions: na, cl, k, negatively charged protein ions (a-) Cl- and na+ more outside, k+ more inside, a- synthesized inside. Unequal disposition: passive differential permeability. K+ and cl- can pass through membrane, na+ has difficulty. Neurotrans can depolarize (decr resting potent) or hyperpolarize (incr resting potent) receptive membrane. Excitatory posynaptic potentials (epsps) = postsynaptic depolarization. Epsps and ipsps are graded responses amplitudes proportional to intensity of signals that. Inhibitory postsynaptic potentials (ipsps) = postsynaptic hyperpolarization elicit them.