BIOL 3096 Chapter Notes -P53, Sarcoma, Mouse Mammary Tumor Virus
3 Mar 2014
School
Department
Course
Professor
Document Summary
Epidemiology: cigarette smoke, coal tars, asbestos, etc. were all found to cause cancer, this led to the discovery of carcinogens. Carcinogens: a type of mutagens- that is substances that cause genetic mutations, the mutations are highly varied from carcinogen to carcinogen. Hereditary cancer: there are not many instances of inherited cancer tendency, examples, retinoblastoma, occurs in children, it was proposed that retinoblastoma was a recessive trait cancer, so it does not show up in all offspring. Viral transmission of cancer: cancer was observed in mice using viral vectors to infect the rodents, the agent of the tumors was found to be transferrable, it could be filtered out of the. Some strains developed tumors, some did not. homogenate. The nucleic acid turned out to be rna, not dna, and the length of the rsv gene was longer than the rav gene.
