BIL 250 Chapter Notes - Chapter 7b: Transposable Element, Insertion Sequence, Transposase
28 Sep 2016
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Transposable element: mobile genetic elements of a chromosome that can move to different locations on the genome. Transpose to or from a cell"s chromosome, plasmid, or phage chromosome. Transpose to or from the same or different chromosomes. Nonhomologous recombination: these transposable elements insert into dna that has no sequence homology with it. The two types of transposable elements: encode proteins (euk and prok, move dna to a new position. Replicate dna and integrate replicated dna somewhere else. Copy and paste mechanism c. encode reverse transcriptase and makes copies of rna transcripts from dna. new dna copies integrated at different sites c. Insertion sequence (is) elements: simplest, found in chromosomes and plasmids, transposase for mobilization and insertion, 768 bp to 5kb, first identified in e. coli. Is ends have inverted terminal repeats (itrs: may. Og copy remains in place while the new one is inserted.
