BIO SCI E109 Chapter Notes - Chapter 5.5-5.7: Phagocytosis, Low-Density Lipoprotein, Pinocytosis

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Chapter 5: transport across the plasma membrane 5. 5-5. 7. *polar or charged solutes that must enter the body cell cannot cross the plasma membrane through passive transport because they will be going against their concentration and electrochemical gradient. Therefore, they will need to undergo a process known as active transport, and this process requires energy to move solutes across the membrane. The 2 major sources of cellular energy are: energy obtained from hydrolysis of adenosine triphosphate (atp) is the source of primary active transport, energy stored in an ionic electrochemical gradient is the source of secondary active transport. Carrier proteins that mediate active transport have binding sites with a high affinity for solute when the binding site faces the low-concentration side of the membrane and vice versa. This is different from carrier proteins of facilitated diffusion because the binding sites will have equal affinity on both sides of the membrane.

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