NURS 3110 Chapter Notes - Chapter 2: Lymphogranuloma Venereum, Chlamydophila Pneumoniae, Chlamydia Trachomatis
Document Summary
Obligate intracellular parasite - cannot synthesize own atp. Developmental cycle - host cell engulfs infectious particles via phagocytosis, host cell forms elementary body, then formed reticule body, then produce multiple elementary bodies released from cell. Cell lyses from pressure, eb phagocytosed by more hosts and cycle continues. Shared group (genus) specific (all chlamydia): lps. Chlamydia reach a balance w/ host prolonged, persistent, infection (subclinical) asymptomatic. Women: urethritis, cervicitis (white discharge), pelvic inflammatory disease (pid), sterility or ectopic pregnancy, many (70%) asymptomatic. Ocular trachoma: leading cause of blindness worldwide. Initial infection - small painless lesions with headache, fever, muscle aches. Granulomas populate in lymph nodes near primary lesion. Inapparent genital lesion heals, enlarged and painful lymph nodes (inguinal) - bubo bursts and heal with scarring that obstructs lymphatic channels of genitalia, anus. To reduce spread but require surgical correction to remove accumulation of granuloma. Surgery to remove lymph nodes that narrow rectum. Associated with upper respiratory infection (pharyngitis, bronchitis)
