MCDB 1B Chapter Notes - Chapter 45: Brown Adipose Tissue, White Adipose Tissue, Autocrine Signalling
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Chapter 42: animal hormones: white fat stores lipids but brown fat metabolizes lipids into heat without producing atp, lean people have more brown fat than obese, excess calories burned by brown fat were responsible for low body mass. In most cases, the complex formed by the lipid- soluble hormone and its receptor acts by altering gene expression in the cell"s nucleus. When insulin is not present, these transporters are returned to the cytoplasmic pool through endocytosis: a high concentration of glucose in the blood increases urine output by two mechanisms. First, it causes water to move from cells into the blood by osmosis, and this increase in blood volume results in increased urine production. Second, the increased glucose in the tubules of the kidneys pulls more water into the urine by osmosis. Diabetic individuals thus can become dehydrated, but more importantly they suffer from a lack of metabolic fuel.