BIOCHEM 524 Chapter Notes -Voltage-Gated Potassium Channel, Lipid Bilayer, Fluid Mosaic Model

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The temp. of transition from an ordered crystalline state to a fluid state in crystalline state, acyl chains pack together in fluid phase methylene groups of acyl chains rotate freely. Chapter 9 notes: membrane transport all animal cells maintain intracellular ion concentrations that differ from those outside the cell the plasma membrane prevents their diffusion. 9. 1 the thermodynamics of membrane transport inside of cell more negatively charged than outside: generates a voltage across membrane, membrane potential ( ) in simplest case = ft. [ x ]out process is spontaneous when x moves from high to low concentration: for ions, membrane potential must be added: +zf : the protein that initially established the ion gradient of the cells is an active transporter requires free nrg of atp to move the ions. 9. 2 passive transport: porins are barrel proteins, porins are trimers where each subunit forms 16 18 stranded membrane-spanning.

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