BIOL 212 Chapter Notes - Chapter 6: Dna Mismatch Repair, Dna Replication, Dna Ligase
19 Feb 2018
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Disease caused by abnormal and uncontrollable cell proliferation followed by invasion and colonization of body sites normally reserved for other cells. Enzyme that reseals nicks that arise in the backbone of a dna molecule; in the laboratory can be used to join together 2 dna fragments Enzyme that catalyzes addition of subunits to a nucleic acid polymer. Collective term for the enzymatic processes that correct deleterious changes affecting the continuity or sequence of a dna molecule. Process by which a copy of a dna molecule is made. Homologous recombination mechanism by which double-strand breaks in a dna molecule can be repaired flawlessly; uses an undamaged, duplicated, or homologous chromosome to guide the repair. During meiosis, the mechanism results in an exchange of genetic information between the maternal and paternal homologs. At a replication fork, the dna strand that is made discontinuously in short separate fragments that are later joined together to form one continuous new strand.
