BIOL 2100 Chapter Notes - Chapter 15: Muscular Dystrophy, Barr Body, X-Inactivation

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Biology chapter 15 textbook notes (the chromosomal basis of inheritance) Chromosomal theory of inheritance : genes have specific positions (loci) on chromosomes, which undergo segregation and independent assortment, segregation of 2 alleles into separate gametes caused by separation of homologs in anaphase i. Independent assortment caused by random arrangement of chromosome pairs at metaphase i. 15. 1 morgan showed that mendelian inheritance has its physical basis in the behavior of chromosomes. Experimentation on fruit fly, drosphilia melanogaster because produce lots of offspring and only 4 pairs of chromosomes. Wild type phenotype commonly observed in nature (red eyes,w+) Mated white male fly with red female fly. F1 offspring all had red eyes, suggesting that red eyes was the dominant trait. Only males got white eyes, assumed that trait was sex-linked. Associated with x-chromosome, because males only have 1 x. Fe(cid:373)ale (cid:272)ould get (cid:449)hite eyes if (cid:271)oth x"s (cid:272)arried the allele.

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