IMED3001 Study Guide - Midterm Guide: Vascular Resistance, Oliguria, Macula Densa
9 Jan 2021
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Main role is to convert angiotensinogen to angiotensin i. Secretion is stimulated by intravascular volume depletion, reduced renal blood flow or reduced sodium presentation to the macula densa. This leads to activation of baroreceptors and the sympathetic nervous system which causes beta1-adrenergic stimulation of the juxtaglomerular apparatus. Arginine vasopressin (avp) or antidiuretic hormone (adh) Regulates renal handling of h20 by increasing h20 permeability of the renal collecting ducts. Reduced ability to excrete free h2o decreased urine output. Increased vasoconstriction but this is usually only a minor effect at physiological levels.
