CELL 1010 Lecture Notes - Lecture 4: Microtubule Organizing Center, Lamin, Intermediate Filament

• School: Tulane University
• Department: Cell and Molecular Biology
• Course: CELL 1010
• Professor: Dr.V

Document Summary

Cytoplasm- everything inside the plasma membrane that includes the cytosol and all organelles. Cytosol: region of eukaryotic cell that"s outside of the cell organelles (membrane-bound structures) but inside the plasma membrane. The cytosol contains complexes (which don"t have membranes) like ribosomes: central coordinating region for many metabolic activities of eukaryotic cells, translation takes place in the cytosol on the ribosome complexes, glycolysis-catabolic process in which sugars are broken down. 13 long proteofilaments forming a single hollow tube. Originates from a complex called the centrosome: microtubule organizing center- > (-) end of microtubule is usually found here (animal cells) Found inside the nucleus; nuclear lamins for a network of intermediate filaments that line the inner nuclear membrane and provide anchorage points for the nuclear pores. Function (-) end below plasma membrane, (+) end stretches to change cell shape. Mobility- cellular tracks to carry cargo; anchor cells together. Cancer metastasizes because of the dynamic nature of actin.