PHYSCI 5 Lecture Notes - Lecture 14: Ulcerative Colitis, Cortisol, Constipation
Absorption
Stomach - want food to be absorbed slowly, not quickly
- Slow absorption because we want to minimize insulin spike
- We want it to be released in small quantities not large
- Causing less insulin increase
- Food is hormonal
- Determines which hormones we are releasing
● Insulin is a hormone that promotes lipogenesis - promote formation of fat and insulin
prevents lipolysis
○ Refined sugar, huge sugar, leading to insulin spike
● What slows insulin spike? Complex sugar that requires longer time to be broken down
and contains fiber
○ Low glycemic load is good, high glycemic load is bad
○ Trick body to minimize spike - white bread, sugar, sweets, -- to decrease the rate
of diseases
Large intestine houses many bacteria
● Releasing the bad chemicals - live inside our bodies - lead to inflammation, immune
system on high alert
Diseases:
● Heartburn - getting burning sensation in throat - hydrochloric acid HCl - way we
measure it is to quantify it, pH=2. Take tums
○ Stomach is equipped to handle HCl, so we always contain it in the stomach
sometimes because changes in organ in the digestive system and the acid leak
upwards to esophagus, and small intestine -- can’t you have bicarbonate
released
● GERD - gastroesophageal reflux disease - acid constantly leaking in the esophagus
○ The stomach is only equipped to buffer acid, but the rest isn’t
● Means that something about our diet is wrong -
○ The acid goes up (esophagus) and goes into the windpipe and trachea to
lung→ eat way before sleeping
Take medication whether they’re feeling heartburn or not && Sleep at an incline
● Ulcer - bacteria, H. Pylori - stomach ulcer, duodenal ulcer
● Celiac disease - celiac screw - does damage to the lining of small intestine →
malnutrition → the good stuff doesn’t get absorbed
- Caused by immune system activities
- Autoimmune system reaction - one reaction is to a protein called gliadin, where
flour come from, rye, barley,
- - gluten free isn’t good for someone , but if you are sensitive to gluten like celiac
(eat bread and then get discomfort) - then you might have celiac, makes a
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Document Summary
Stomach - want food to be absorbed slowly, not quickly. Slow absorption because we want to minimize insulin spike. We want it to be released in small quantities not large. Insulin is a hormone that promotes lipogenesis - promote formation of fat and insulin prevents lipolysis. Refined sugar, huge sugar, leading to insulin spike. Complex sugar that requires longer time to be broken down and contains fiber. Low glycemic load is good, high glycemic load is bad. Trick body to minimize spike - white bread, sugar, sweets, -- to decrease the rate of diseases. Releasing the bad chemicals - live inside our bodies - lead to inflammation, immune system on high alert. Heartburn - getting burning sensation in throat - hydrochloric acid hcl - way we measure it is to quantify it, ph=2. Gerd - gastroesophageal reflux disease - acid constantly leaking in the esophagus. The stomach is only equipped to buffer acid, but the rest isn"t.
