BCMB30011 Lecture Notes - Lecture 2: Starch, Isomer, Duodenum

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* half the story is digestion (chopping up the macromolecules into smaller molecules), and the other half of the story is being able to absorb the digested molecules into the circulation. * absorption includes movement across a membrane/lipid membrane. The gut has an epithelial layer/colonic cells that line the small intestine that separates the inner part of the gut where the digestion is occurring from the inside of the body where the circulation is. In some cases, this is an active transport process which requires atp. * the ability to absorb molecules relies on the presence of transporters and these transporters during evolution arose in context with the diet that was available at the time. Relevance of understanding biochemistry of digestion and absorption: molecular understanding of a basic physiological process understand how the system works, allows us to understand the basis of starvation/undernourishment. * calorie expenditure > calorie intake = lose weight.

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