BIOL10003 Lecture Notes - Lecture 15: Cpg Site, Huntingtin, Fetal Alcohol Spectrum Disorder

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Lecture 15 genetics and the study of variation. The genetic constitution of an organism. phenotype. The morphological, biochemical and behavioural properties of an organism resulting from a specific genotype and its interaction with the environment genome. The total amount of genetic material in a chromosome set (in humans - one set of chromosomes) Sequencing a genome is working out the base sequence (adenine, thymine, cytosine and guanine) of the dna. It does not tell the function of the sequence. Drinking during pregnancy fasd, fas (fetal alcohol spectrum disorder, fetal alcohol syndrome) Growth retardation, characteristic facial features, and central nervous system anomalies (intellectual impairment) Found in children whose mothers had a history of heavy alcohol use or frequent heavy intermittent alcohol. However, alcohol metabolism is genetic, which is a confounding genetic variable: genetic factors. Hu(cid:374)ti(cid:374)gto(cid:374)"s disease gene for huntingtin protein is on chromosome 4 (x) - we all have two copies of the gene.

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