BIOL10005 Lecture Notes - Lecture 5: Sexual Differentiation, Attention Deficit Hyperactivity Disorder, Epistasis

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Antigen: any molecule which induces an immune response (antibody generator) The alleles determine the presence or absence of an antigen on the surface of the red blood cell. The antigen is a glycoprotein embedded in the red blood cell membrane. If you have antigen a -> type a. Alleles determine the presence/absence of an antigen embedded in the red blood cell membrane. The antigen is a glycoprotein to which sugars are attached. Type o people have only antigen h (no complete conversion) Unique system because of the presence of antibodies in the plasma. Agglutination of the red blood cells when mixed with antibody a or antibody. B determines which antigens are present ie. blood type. Antigen on surface of rbc forms chemical association with antibody and clumps the red blood cells together. Key factor is antigen on surface of rbcs of the donor.

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