BIOL10005 Lecture Notes - Lecture 2: Cystic Fibrosis, Exocrine Gland, Breast Cancer

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Teens that mothers had high stress levels during pregnancy have more methylation in the promoter region of glucocorticoid receptors. Child abuse leaves epigenetic marks -> different patterns of dna methylation and gene expression compared to those who were not. Learning outcomes: structure of dna, prokaryotic dna replication, similarities/differences of eukaryotic and prokaryotic dna replication, replication of telomeres. Chameleons changes colour based on the mood/environment. Octopus can change colour based on light sensitive proteins. Igua(cid:374)a"s (cid:272)olour is i(cid:374)flue(cid:374)(cid:272)ed (cid:271)y the algae they eat. Polymorphisms: variations with no differences to viability. Tongue rolling: variations that affect health. Mutation in genes that transports chloride ions across the cell membranes primarily affects the lungs and the digestive system due to malfunctioning of exocrine system. Collagen defect hyper flexibility and no firmness in the skin. Mutations occur in any organisms and variations happen at different stages of development: big medical question: curing cancer. Cancer is associated with changes in dna in somatic cells.

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