NEUR30003 Lecture Notes - Lecture 17: Neurotrophic Factors, Cluster Headache, Gout

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Sex, steriods and the nervous system: defining the basics: * (cid:373)ost (cid:272)o(cid:373)(cid:373)o(cid:374)l(cid:455) (cid:396)efe(cid:396)s to (cid:272)h(cid:396)o(cid:373)oso(cid:373)al se(cid:454) (cid:894)i(cid:374)di(cid:448)idual"s se(cid:454) (cid:272)h(cid:396)o(cid:373)oso(cid:373)es(cid:895), sometimes referred to as genetic sex xx or xy. * other terminology does not always correlate with chromosomal sex such gender, sexual identity, and sexual orientation, so terms should not be used interchangeably. For example, gender identity = feeling of belonging to a particular sex, sexual orientation= erotic responsiveness towards a particular sex these may differ from chromosomal/genetic sex. * other cell types may change too such as hair follicles etc. that change with respect to genetic sex. But, having the sry gene is critical to going down one line to make a testes or the other line if you do(cid:374)"t ha(cid:448)e it, to (cid:373)ake a(cid:374) o(cid:448)a(cid:396)(cid:455) * sex steroids are androgens (like testosterone), estrogens (like estradiol) and progesterone. * primary source sex steroids = gonads (testes & ovaries).

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