NEUR30003 Lecture Notes - Lecture 2: Luigi Galvani, Positive Feedback, Cortical Map

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Lecture 1. 2: the huge interest in electricity in the 18th century included investigation into what its effect was on the body. Galvani discovered, sometime around 1780, that electrical stimuli where much more effective in contracting a muscle if they are applied to the muscle"s nerve rather than directly to the muscle, and postulated that nerves contain or conduct "animal electricity". The microscopic details of neural architecture started to be revealed around 1840s and because increasingly clear with the development of silver stains by. Much of the evidence for synaptic transmission came from studies of how nerves affect peripheral targets; how motor nerves signalled to skeletal muscle and how the sympathetic and parasympathetic nerves affected target organs in the body. Spirits running through hollow nerve fibres, conveying impressions to the brain and activating muscles (descartes) Mini explosions caused by fermentation upon the mixing of fluid droplets from the nerve ends and blood, activating muscle (willis)

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