NEUR30003 Lecture Notes - Lecture 3: Synapsis, Otto Loewi, Neuron Doctrine
13 Aug 2020
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Charles serrington supported the neuron doctrine even before cajal"s evidence led to abandonment of reticular theory. 1897: sherrington proposed there must exist a junction b/w neurons, and proposed the term synapsis -> later became synapse. Must be a physical gap b/w cells. Purely hypothetical entity in that there was no way to see one until the 1950s when. Ideally characterized by chemical transmission step (slower process not electrical) electron microscopes were invented. Switches can be combined to make logical elements or logic gates. Transistor = semiconductor can form integrated circuits it is a switch. If condition met -> signal passed on (etc. ) As well as transmission of signals, the cells of the nervous system must also integrate, process, and store info. The points of control over info transmission are the connections b/w neurons, the synapses. Gap b/w the 2 neurons chemicals cross from pre- synaptic terminal to post-synaptic terminal: very dark because it contains lots of proteins.
