NEUR30003 Lecture Notes - Lecture 25: Substance Abuse, Impact Factor, Central Canal
Mental and neurological disorders classified into 4 categories by who: Learning and developmental disabilities include functional limitations that manifest in infancy or childhood as a result of disorders of or injuries to the developing nervous system. Distinction based on what were thought to be disorders caused by an organic process , such as degeneration or inflammation (neurological disorders) and disorders of the mind (mental disorders) due to it not working properly rather than being damaged. Most significant are: alzheimer"s disease and other dementias, epilepsy, parkinson"s disease, stroke, multiple sclerosis (ms) Dementia is a deterioration of intellectual function and other cognitive skills that is of sufficient severity to interfere with social or occupational functioning. Alzheimer"s disease is the most common form of dementia. Deposition of amyloid protein and the disruption of the neuronal cytoskeleton. Microtubules important: tau is a microtubule associated protein (map, abnormality in the way tau aggregates overproduction -> multimers form that aggregate and don"t get processed.