NEUR30003 Lecture Notes - Lecture 24: Dopamine Agonist, Substantia Nigra, Dopaminergic Cell Groups
13 Aug 2020
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Pleasure is good, and pain is bad (path to greater pleasure may involve enduring pain) Fear and anxiety are the greatest obstacles to happiness. We should be looking to achieve what we are capable of, our ergon requires utilization of our intellect to reason and seek the best path and situation. Life expectancy in us has fallen for the last 3 years mainly attributed to hedonic drugs. 2mg of opium is fatal for most people. Mostly middle-class white males die from overdoses. Drug addiction: a pervasive neuropsychiatric disease that imposes immense personl and societal costs. Rat brain shows where heroin binds (dark regions: suggests where endogenous factors must interact with these structure, discovery of opioid peptides. Sites in the brain that produced huge self-stimulation responses included a path from the ventral medial forebrain to the rostral brainstem, centred around a fibre tract called the median forebrain bundle.
