PHYS30005 Lecture Notes - Lecture 17: Motor Neuron, Skeletal Muscle, Ventral Root Of Spinal Nerve

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Not just for locomotion: essential for life, eg. breathing diaphragm. Loss of muscle impacts health: muscle as endocrine organ, essential for survival. Functional independence: health span / healthy ageing, capacity to do work/play, qol, adl. Reinforce concept of sarcopenia as a neuromuscular syndrome. By 2050, world"s population over 60 years will double from ~11% to 22% By 2050, 80% of older ppl will live in low- and middle-income countries. Increase in number of ppl in older age groups is associated with increase in life expectancy. Ageing associated with increased incidence of chronic health conditions and increase prevalence of impairment and disability: eg. visual and hearing impairments, cognitive decline, musculoskeletal disorders, frailty, and sarcopenia. All reduce activity and restrict participation in personal, work-associated and social activities. Frailty and weakness high risk of mortality, falls, institutionalisation and hospitalisation. Age-related loss of skeletal muscle mass and function.

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