PHYS30005 Lecture Notes - Lecture 4: Exercise Intensity, Citric Acid Cycle, Institute For Operations Research And The Management Sciences

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Online lecture 4 measuring substrate utilization during exercise. Carb and fat are the main substrates for muscle contraction. Exercise intensity: highest: carb oxidation is higher than fat oxidation. Rer informs about whether atp is being produced by fat or from cho sources. Rer doesn"t inform if the cho (or fat) is from the circulation or intramuscular sources. Example: glucose (can come from circulation (extracellular glucose) but also stored as glycogen in the muscle (intracellular glycogen): go through glycolysis -> tca cycle -> produce. Nadh -> used in etc to produce atp. Example fat: can enter the cell as ffa or derived from intramuscular triglyceride (imtg) To identify intracellular or extracellular sources of substrate for atp production, it is necessary to use. High intensity: muscle glycogen is biggest contributor, plasma ffa contribute a little bit more than muscle derive fat. *** muscle uses more glycogen and less fat higher exercise intensities.

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