MEDI251 Lecture Notes - Lecture 11: Positive And Negative Predictive Values, Pap Test, Mammography
Document Summary
Validity of dietary assessment methods including sensitivity and specificity. Understand how to calculate sensitivity and specificity, negative predictive value, positive. Identify different dietary assessment methods available and their potential for error. Population screening: application of a test to asymptomatic people to detect occult disease or a precursor state, e. g pap smear, mammography. Requirements for a screening program: suitable disease, suitable test, suitable program, good use of resources. Phenomenon of disease: natural history: disease is a process that unfolds over time, natural history sequence of developments from earliest pathogical change to resolution of disease od death. Incubation = time to symptoms (infectious disease: latency = time to detection (for non infectious disease) or to infectiousness. Infectious disease = becoming infected to becoming infectious: natural history is central to screening: Screening test: reliable get same result each time, validity get the correct result, sensitive = correctly classifies cases, specificity = correctly classify non-cases.