PHTY200 Lecture Notes - Lecture 11: Shortness Of Breath, Muscle Hypertrophy, Goblet Cell
Document Summary
Obstruction is something in the airway lumen (secretions), something narrowing the airway lumen (bronchoconstriction, oedema), reduced stability of the airway wall. Bronchitis most days for at hypertrophy and least 3 month in hyperplasia. Increased airflow obstruction to expiration swelling, sputum. Hyperinflation (irreversible) bronchial lumen use least 2 reduced in number. Impaired secretion movement mcc, secondary cough chronic production of mucus. Wheeze number and hence mucociliary escalator less effective. Dyspnoea the air spaces airway walls expiration causes floppy. Antitrypsin attractants which reduce activity of use terminal. Gas trapping / hyperinflation (irreversible) altered chest. Antitrypsin is a protease inhibitor breathing which reduces the function of the. Intercostal their walls wall and muscle mechanics enzymes responsible for the indrawing. Imbalance of protease- problems if cough (secondary antiprotease leads to destruction affect) of elastin. Resultant parenchymal destruction results in enlargement of alveolar spaces distal to terminal bronchioles. Oedema of the by inflammation bronchial wall and bronchospasm of the airways.
