PHTY300 Lecture Notes - Lecture 1: Perfusion, Vasodilation, Metabolic Acidosis

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26 Jul 2018
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Why are the results helpful: initial results. What system might be responsible? (respiratory or metabolic) Is this an acute or a chronic condition: over time. Systems respiratory and renal (metabolic) systems control acid-base balance/homeostasis. Bi-carbonate ions controlled by renal (metabolic) system. Decreased gas movement overall: low tidal volume without increased rr, low rr without increased tidal volume. Signs & symptoms of respiratory acidosis: cerebral vasodilation & increased icp, drowsiness/confusion, headache, unsteady/falls. Acid gain or bicarbonate loss: diabetic ketoacidosis, methanol poisoning, lactic acidosis (decreased o2 to tissues, starvation, renal failure, severe diarrhoea. Signs & symptoms of metabolic acidosis: cardiac arrhythmias, decreased contractility, hyperventilation, confusion, drowsiness, decreased renal blood flow. Hyperventilation (blowing off too much co2: anxiety, pain, acute (severe) hypoxaemia, sepsis. Signs & symptoms of respiratory alkalosis: tingling lips, fingers, cerebral vasoconstriction. Acid loss (or bicarbonate gain: gastroi(cid:374)testi(cid:374)al vomiting, nasogastric suction, re(cid:374)al metabolic syndromes, drugs (including over diuresis) not renal failure.

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