BCCB2002 Lecture Notes - Lecture 1: Glycogenin, Amylose, Cotransporter
Document Summary
Involves an attack by the inorganic phosphate (pi) on terminal 1-4 glycosidic bond: preserves some of the energy of the glycosidic bond: If glucose was the produce and we were going to use if for glycolysis, we would need to use atp to phosphorylate the glucose to produce glucose 6- phosphate: hydrolysis: Involves attack by water on 1-4 glycosidic bond. 6 glycosidic bond: debranching enzymes are involved in two activities, transfers three of the remaining four glucose residues to a linear portion, hydrolyses the 1-6 bond releasing glucose. Instead of km (which is use for enzymes), we use kt for glucose transporters: assuming the [s]in = 0, when [s]out = kt the rate of substrate uptake is half of, glucose transporter 2: Vmax: has a high kt of 17 mm, this means that the concentration of the glucose in the blood needs to be. 17 mm for the transporter to be working at half its maximal rate of transport.
