GMED2000 Lecture Notes - Lecture 7: Posttraumatic Stress Disorder, Depression And Anxiety, Adrenal Medulla

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A person experiences stress when a demand exceeds a person"s coping abilities, resulting in reactions such as disturbances of cognition, emotion and behaviour that can adversely affect well being. Worked to discover a new sex hormone. Development of bleeding ulcers in the stomach and duodenal lining. Dr selye witnessed these changes with many agents and called these stimuli. Selye termed this general response general adaptation syndrome (g. a. s) Stage of resistance or adaptation: mobilisation contributes to fight or flight. Stage of exhaustion: progressive breakdown of compensatory mechanisms. Stressor triggers the hypothalamic-pituitary-adrenal (hpa) axis activates sympathetic nervous system. Begins with the actions of the adrenal hormones cortisol, noradrenaline, adrenaline. Occurs only if stress continues and adaptation is unsuccessful onset of disease. Anything that demands a response in order to maintain homeostasis: Noxious: pain, cold, trauma, hunger, electric shock. Not noxious: life events, exams, excitement. Interaction of consciousness, the brain and spinal cord and the body"s defence mechanisms.

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