HUMB1001 Lecture Notes - Lecture 2: Loose Connective Tissue, Matrix Similarity, Skeleton

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There are four connective tissue types that form the skeletal system: bones, cartilage, tendons, muscles. Overall the main functions of the skeletal system are: support, protection, assistance with movement, mineral homeostasis, blood cell production, triglyceride storage. Only once fully surrounded by matrix, and trapped in a space called a lacunae, is a cartilage cell referred to as a chondrocyte. Proteoglycan aggregates function as minute sponges capable of trapping large quantities of water this gives cartilage its ability to spring back after being compressed and hence its strength. As a result of these characteristics, metabolically cartilage is fairly inactive: therefore, it is also very slow to repair after damage as the nutrients required to assist in this repair cannot reach the damaged area easily. Cartilage grown in two main ways: appositional growth cartilage is added to the outside of the existing cartilage. Interstitial growth chondrocytes within the matrix divide and add more matrix between the chondrocytes.

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