SLE221 Lecture Notes - Lecture 2: Hematopoietic Stem Cell, Neutrophil Extracellular Traps, Hematocrit

• School: Deakin University
• Department: Science, Engineering and Built Environment
• Course: SLE221
• Professor: Jan West

Document Summary

List and describe the composition of the blood, including the components of the plasma. Blood is of extracellular fluid and 8% of total body weight. Erythrocytes (45%: buffy coat (<1%) which contains platelets and leukocytes. Functions: blood clotting defence against foreign invades, hormones, enzymes and increase osmotic pressure which causes blood to be pulled into the capillaries. Types: albumins: most abundant, transport substances and contribute to osmotic pressure, globulins: Alpha (most abundant) and beta: transport water-insoluble substances including clotting factors and inactive precursor molecules: gamma: antibodies. Fibrinogen: inactive precursor for the fibrin meshwork of a clot: dissolved organic molecules, ions, trace elements, vitamins and dissolved gases. (1%) The different types of cells found in blood and how they are produced. Function: o2 transport and use glucose to produce energy. Biconcave disc and large surface area for diffusion of o2. Flexible membrane allows rbcs to travel through narrow capillaries without rupturing: haemoglobin: iron-containing pigment only in rbcs.