MMED1005 Lecture Notes - Lecture 24: Macrophage, Myenteric Plexus, Jejunum

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Introducing your gut:
- Function and organisation of the gut
- Gross anatomy
- Finer structure
- Gut motility how it works
- The mucosa
- Stomach, gastric acid
- Pancreas and digestion
- Bile and the digestion of fats
- Portal circulation and the liver
- Colon and fluid movements
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Why do we eat?
- Because we get hungry?
o Hunger is a sensation that has evolved to ensure that we feed adequately to
meet specific needs
- We eat because we need:
o Energy for cellular processes (e.g.: ion pumps, anabolic processes, muscle
contraction) and physical work
o Raw materials (amino acids, fats, minerals, vitamins, etc.) for:
Tissue growth
Tissue repair
Tissue replacement
Eating is hazardous because:
- Looking for food puts us at risk of predation
- Food can contain toxins or sharp bits
- Food may contain micro-organisms and fight back
- Our own digestive processes can digest our own body tissue
- We can lose phenomenal quantities of fluid if anything goes wrong
Functions of the gut:
- Motility propulsion and mixing
o Directly controlled (movement-to-movement)
- Secretion mucous, acid, enzymes, etc.
o Directly controlled
- Blood flow needs to increase during secretion and absorption
o Directly controlled
- Digestion what happens when secretion and motility work together, i.e. digestion
is the breakdown of the food particles and then the absorption of those nutrients
o NOT directly controlled
- Absorption and processing how food gets to your body via the bloodstream
o Not much directly controlled
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Document Summary

Because we get hungry: hunger is a sensation that has evolved to ensure that we feed adequately to meet specific needs. We eat because we need: energy for cellular processes (e. g. : ion pumps, anabolic processes, muscle contraction) and physical work, raw materials (amino acids, fats, minerals, vitamins, etc. ) for, tissue growth, tissue repair, tissue replacement. Looking for food puts us at risk of predation. Food can contain toxins or sharp bits. Food may contain micro-organisms and fight back. Our own digestive processes can digest our own body tissue. We can lose phenomenal quantities of fluid if anything goes wrong. Motility propulsion and mixing: directly controlled (movement-to-movement) Secretion mucous, acid, enzymes, etc: directly controlled. Blood flow needs to increase during secretion and absorption: directly controlled. Digestion what happens when secretion and motility work together, i. e. digestion is the breakdown of the food particles and then the absorption of those nutrients: not directly controlled.

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