1041SCG Lecture Notes - Lecture 4: Endergonic Reaction, Ribose, Organic Compound

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Metabolism: metabolism is the sum of all chemical reactions performed by a cell or organism. Individual reactions are catalyzed by specific enzymes and connected into metabolic pathways, where the product of one pathway becomes the substrate for others. These pathways can be linear, reversible, circular, branched: anabolism (biosynthetic) is the synthesis of compounds and molecules from simpler ones. Gproduct > gsubstrate so g > 0. Product has more energy than the initial substrate: catabolism (degradative) is the breakdown of compounds and molecules into simpler ones. Gproduct < gsubstrate so g < 0. Gibbs free energy (g: the energy stored within a system = g, the more complex systems have more g, change in system energy = Work in a cell: cells perform three kinds of work that require energy. Mechanical: contraction of muscle cells, movement of chromosomes, beating of cilia. Transport: pumping across membranes against the concentration gradient: energy for work is atp.

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