BIOM20001 Lecture Notes - Lecture 62: Type Iii Hypersensitivity, Vasodilation, Apitoxin

74 views10 pages
6 Oct 2018
Department
Course
Professor

Document Summary

Immunity: provides protection against infection; mediated by cells of the immune response. Humoral immune response - extracellular pathogens: antibodies neutralize microbes, block infection, promote phagocytosis. Cell mediated immunity - cell-associated microbes: cd4+ helper t-cells secrete (cid:272)ytoki(cid:374)es to (cid:858)help(cid:859) b-cells and macrophages; cd8+ cytotoxic t-cells kill infected cells. Antigen recognition --> proliferation --> differentiation --> eliminate antigens --> most die by apoptosis --> surviving memory cells. Immune mediated injury: caused by too much or too little immune response. Microbe - immune response excessive or microbe persistent. Environmental antigens: immune response towards noninfectious and harmless antigens. Antibody-mediated (type ii): igg and igm antibodies directed to cellular antigens. Immune complex-mediated (type iii): circulating igg and igm form complexes with antigen and are deposited. T-cell-mediated (type iv): cd4 and cd8 t-cells and macrophages. Atopic individual often develop multiple types of allergic disease (eczema, rhinitis, asthma). Non-atopic individuals may develop allergy to single antigen (penicillin, bee venom)

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions