MIIM20002 Lecture Notes - Lecture 25: Genital Wart, Wart, Cell Culture

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Papillomaviruses: small dsdna viruses are species and site specific replicate only in skin produce warts sometimes produce cancers each mammal has some don"t grow in cell culture over 100 different genotypes of hpv. Can"t serotype because to do that we need serum raised in animals. But we can"t produce it in animals very well. Instead its easier to identify it by sequencing dna. 4 main groups in man: cutaneous warts (hpv 1,2) genital warts (hpv 6,11): more serious genital cancers (hpv 16,18) Over the past 3 decades, the incidence of genital warts has risen faster than that of genital herpes. Genital warts are now the single most common sexually transmitted infection to lead people to seek medical advice. Genital warts are second only to chlamydial infections as the most common std; 79% of women may have genital hpv infection at some time in their lives. However, many people become infected with hpv during their lifetime without exhibiting symptoms.

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