MIIM20002 Lecture Notes - Lecture 30: Warsteiner, Elisa, Legionella
4 Aug 2018
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>90% cases caused by legionella pneumophila (nearly all are serogroup 1 - particular lps) an emerging pathogen because we only recognise it as a pathogen recently. Gram negative soil/water organism - not a natural human pathogen. Most ppl infected should be able to clear it easily so we don"t see that many cases. Philadelphia, usa, 1976, american legion convention, 182 cases, 29 deaths. Netherlands, 1999, whirlpool spa at frisian flower show, 242 cases, 28 deaths. Melbourne, australia, 2000, aquarium outbreak, 113 people, 2 deaths. Murcia, spain, 2001, cooling towers, 449 cases, 6 deaths. Wesley hospital, qld, 2013, showers, 2 cases, 1 death. Warsteiner brewery, germany 2013, 165 cases, 2 deaths. Charcoal detoxifies products of bacteria requires high levels of cysteine and iron for growth. Good because they can penetrate into host cells urine antigen test for diagnosis. Does(cid:374)"t (cid:374)eed to (cid:271)e i(cid:374) (cid:271)ody survives and replicates within alveolar macrophages and amoebae.
