PHYS20008 Lecture Notes - Lecture 27: Pituitary Gland, Vasoconstriction, Osmoreceptor

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* sodium is our most abundant extracellular solute, and it is very important for the movement of other solutes and water around our body. * we get/input sodium most of the sodium from our diet (food & drink), but in certain cases such as diarrhoea or bouts of vomiting you could get sodium intravenously through an iv of saline. * the output of sodium is using through the urine, but we lose some sodium through faeces and the skin. * when salt is ingested without water, there is no change in volume, but the osmolarity increases (the amount of solutes in plasma has increases) * there are a number of homeostatic responses to this: Secrete adh or vasopressin which causes kidneys to reabsorb more water causing conserving of water. * osmolarity is prioritsed over volume, it can day days for the kidneys to exrete salt and water to return the ecf volume back to normal.

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