PHYS20008 Lecture Notes - Lecture 6: Acetylcholinesterase, Central Nervous System, Ligand-Gated Ion Channel

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* a synapse is the space between the end of the neuron that just carried the action potential to the next structure in line e. g. another neuron, skeletal muscle, gland, organ etc. *glutamate is the most common excitatory neurotransmitter in the body when glutamate is released and binds with its receptor in the post synaptic cell, it increases the likelihood that the post synaptic cell will fire an action potential. * there are two main types of glutamate receptors ionotropic and metabotropic. * ionotrophic glutamate receptor receptor that in itself in an ion channel. * metabotropic glutamate receptor the re(cid:272)eptor gets sti(cid:373)ulated (cid:271)ut it does(cid:374)"t ha(cid:448)e a(cid:374) i(cid:373)(cid:373)ediate effect. This causes a series of events inside the cell that alter something e. g. opening a neighbouring ion channels or more complicated things etc. * gaba most common inhibitory neurotransmitter in the body prevent cells from reaching threshold. Gaba receptors open up a chloride channel for chloride ions to move through.

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