PHYS30005 Lecture Notes - Lecture 9: Lactic Acid, Vasodilation, Angiogenesis

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Oxygen uptake during exercise is dependent upon exercise intensity and duration. The oxygen deficit is due to a delay in oxygen delivery and/or mitochondrial respiration. Cp utilisation and anaerobic glycolysis provide energy during this period. Vo2 drift = i(cid:374)(cid:272)rease a(cid:271)ove (cid:858)(cid:373)a(cid:454)i(cid:373)al(cid:859) o2 (cid:272)o(cid:374)su(cid:373)ptio(cid:374) due to ther(cid:373)oregulator(cid:455) (cid:272)o(cid:374)strai(cid:374)ts i. e. do(cid:374)(cid:859)t get steady state. O2 uptake i(cid:374)(cid:272)reases a(cid:374)d sta(cid:271)ilises at a(cid:271)out 80% (cid:894)(cid:858)(cid:373)a(cid:454)i(cid:373)al(cid:859)(cid:895) i(cid:374) high-level marathon runners for at least an hour and a half of continuous exercise. Vo2 drift occurs after this due to factors within the contracting skeletal muscles: recruitment of lower efficiency type ii fibres, reduced p-o coupling efficiency, elevated muscle temperature. Excess post-exercise oxygen consumption (epoc) has three distinct time courses and it due to a slow decline in oxygen demand, resynthesis of key substrates and elevated temperature and hormones. Key role of ventilation (v) is to maintain arterial o2 saturation and remove co2. Breathing frequency and tidal volume increase during exercise i. e. v = tv x rr.

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