PSYC30018 Lecture Notes - Spring 2018 Lecture 15 - Insular cortex, Yohimbine, Lorazepam
Document Summary
Cognitive neuroscience methods examining the executive function of performance monitoring, performance monitoring, dynamic human behaviour requires feedback on the appropriateness of behaviour. Identification and correction of differences between an intended and executed response: error-related negativity (ern) eeg and fmri, occurs in the medial frontal region ~50 100ms after making an error, schizophrenia patients show a diminished error-related response. They also show a diminished rabbitt effect (post-error slowing of responses) Verbal self-monitoring and auditory verbal hallucinations if patients are not detecting their mistakes, these mistakes may be contributing to their delusional behaviour. Difficulty detecting errors in own voice is related to experiences of delusions of alien control -> errors in working memory contribute to delusions. Not limited to schizophrenia also observed in alzheimer"s, borderline personality disorder, adhd, cocaine use and alcohol consumption fmri angular cingulate activated when aware that an error has been made. Undergraduates with obsessive-compulsive personality hyperactive ern is also observed.
