BMS2021 Lecture Notes - Hydrolysis, Death Effector Domain, Granzyme B

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Discuss the basic principles of cell growth and cell division. Cells reproduce by duplicating their contents and then dividing into two new cells. While the details of cellular replication can vary among different organisms, certain characteristics are universal. The dna must be faithfully replicated, the replicated chromosomes must be segregated into two daughter cells and the majority of cells, double their mass and duplicate all their cytoplasmic organelles in each cycle. This follows the general strategy of; cell growth and chromosome replication, chromosome segregation and finally cell division. Chromosomes are made up of dna, complexes with proteins in highly organised structures. The length of a single dna molecule in the average human chromosome is ~3cm. Discuss the stages of the eukaryotic cell cycle. The major events of the cell cycle are chromosome duplication, mitosis and eventually cytokinesis. The cell cycle consists of four distinct stages, g1 phase, s phase (synthesis), g2 phase (collectively known as interphase) and m phase (mitosis).

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