BMS2021 Lecture Notes - Glut2, Glucokinase, Insulin Resistance

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Explain how metabolic processes are divided among specialised tissues and organs. In the average adult male there are both circulating energy as well as stored fuel reserves. Usually there is circulating 20g of glucose, 0. 3g of free fatty acids and 3g of triacylglycerols. Stored fuel is located in three areas, the liver, the muscle and in adipose tissue. Within the liver there is 75g of stored glycogen. This can undergo a metabolic process called glycolysis that restores aa falling bold glucose level. Within the muscle there is 250g of stored glycogen, though this is not accessible for blood glucose, instead glycogen in the muscle is aids in generation of atp to aid in muscle contraction. The muscle also contains 6kg of muscle that can also be used to produce energy. Adipose tissue contains 15kg of fat to use as an energy source. These measurements of course are based on an average male.

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