DEV2022 – Lecture 14
The intestinal epithelium is a highly dynamic tissue:
Crypt is where the stem cells are lined, and it is where cell division occurs.
Stem cells generate all 4 differentiated cells in the intestinal epithelium:
Stem cells gives rise to the transit-amplifying compartment where these cells
undergo rapid cell division. And then these cells give rise to the 4 cell lineages
where they migrate upwards.
Enterocytes = most abundant cell types
The cell is packed with mucins, which provides lubrication and protection on the