DEV2022 Lecture Notes - Lecture 14: Colorectal Cancer, Virtual Colonoscopy, Paneth Cell
Document Summary
The intestinal epithelium is a highly dynamic tissue: Crypt is where the stem cells are lined, and it is where cell division occurs. Stem cells generate all 4 differentiated cells in the intestinal epithelium: Stem cells gives rise to the transit-amplifying compartment where these cells undergo rapid cell division. And then these cells give rise to the 4 cell lineages where they migrate upwards. The cell is packed with mucins, which provides lubrication and protection on the bowel surface. They are a lot of goblet cells present, because you need lubrication. Polyps and tumors in the bowel bleed a lot. Bowel contents are sent in to see if blood is present. The current incidence of colorectal cancer up to age 85 in australia is approximately:
