BMS1062 Lecture Notes - Lecture 31: Telomere, Malaria, Phagocytosis
14 Aug 2018
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Document Summary
Lecture 31 : dna recombination in parasitic antigen diversity. Review the generation of diversity in the immune system by vdj recombination. Evading the immune system by creating antigenic diversity of variant surface glycoprotein (vsg) The mechanisms of antigenic diversity - gene conversion. Plasmodium (malaria) evading the immune system by creating antigenic diversity of p. falciparum erythrocyte membrane protein 1 (pfemp 1 ) Parasites : definition : an organism which feeds/lives off another organism without conferring any benefit to the host. Parasitology study of unicellular or multicellular organisms that have a parasitic cell cycle. Trypanosomes causes african sleeping sickness,chagas diseases and diseases in cattle. Insect host = tsetse fly upon biting an mammalia host, fly is infected parasite develops and migrates to salivary glands of fly. Fly bites new mammalian host, the parasite is then injected into the bloodstream parasites start multiplying within the new host.
