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Class Notes (1,044,359)
AUS (35,215)
Monash (3,700)
DEV (13)
DEV2011 (13)

Class Notes for DEV2011 at Monash University

Early human development from cells to tissues

DEV2011 Lecture Notes - Lecture 12: Basal Lamina, Salivary Gland, Perception

Lecture 12 Epithelial Tissues What is an Epithelial Cell? Lack mobility Organised into closely adherent sheets polarised in apicalbasal orientation Derived from all 3 germ layers Form a barrier between outside world and bo...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 13: Peripheral Nervous System, Myocyte, Oligodendrocyte

Lecture 13 The Nervous System Cellular Diversity Neurone o Fundamental unit of nervous systems o Formed of a cell body from which extend processes o Lots of dendrites but single axon Axon transports nervous message from ce...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 14: Neural Tube, Neoteny, Retroflex Consonant

Lecture 14 Neural Tube Development: Defects and Disorders Neural tube Closure Defects Principles of Neural Tube Closure o Starts from middle of neural tube o Propagates bidirectionally in AP axis o Following closure tube i...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 5: Spermatocyte, Oogenesis, Synapsis

Lecture 5 Fertilisation and Embryo Cleavage Meiosis Occurs within two cell types: o Cells undergoing spermatogenesis o Cells undergoing oogenesis Reduction division Start with parent cell form cells with half genetic compo...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 10: Yolk Sac, Syncytiotrophoblast, Placenta

Lecture 10 Placenta and Extraembryonic Membranes Uterine Receptivity Menstrual cycle is under control of ovarian hormone cycle Day 1: menses: drop of progesterone (sheds endometrium) o Uterus undergoes proliferation ot reb...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 7: Yolk Sac, Epiblast, Hypoblast

Lecture 7 Embryo, Gastrulation and Germ Layers Differentiation Lineage specification and restriction of developmental potential Totipotent cells of epiblast differentiate and become more restricted in their developmental p...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 2: Rudolf Virchow, Fluid Mosaic Model, Robert Hooke

Lecture 2 Cells: Organelles and Functional Compartments Mammalian Cell Robert Hooke (17 century) o Discovered piece of cork was composed of cells Cell Theory (Rudolf Virchow 1859) 3 basic components o All organisms are com...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 3: Confocal Microscopy, X-Ray Microtomography, Electron Microscope

Lecture 3 Imaging Macroscale Imaging Ultarsound o Originally used to detect flaws during ship building o Standard tool for tracking development of babies Detects early signs of serious developmental abnormality immediate s...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 8: Prdm1, Yolk Sac, Somatic Cell

Lecture 8 Germ Lineage and Sex Determination Specification, proliferation, maintenance and differentiation of primordial germ cells have profound bearing on number and function of future germ cells Muticellular eukaryotes ...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 9: Paracrine Signalling, Cell Signaling, Transforming Growth Factor Beta

Lecture 9 CellCell Communication in Development Signaling Signalling core: complexity of networks Drives development to form different structures Defects in signalling pathways Cell communication essential for tissue and o...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 11: Lateral Plate Mesoderm, Notochord, Somite

Lecture 11 Notochord and Somites Mesodermal fates Chordamesoderm notochord o Once mesoderm is generated through gastrulation begins to specialise Specific regions of mesoderm generated become molecularly and morphologicall...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 6: Seminiferous Tubule, G1 Phase, Bone Marrow

Lecture 6 Cell Death and Proliferation Role of both Proliferation and Regulated Cell Death in Normal Development and Adult Homeostasis In renewable tissues, cells that die or are exported must be replaced: o Skin replaced ...

Developmental Studies
DEV2011
Julia Young
DEV2011 Lecture Notes - Lecture 4: Stem Cell, Model Organism, Zebrafish

Lecture 4 Evodevo and Model Organisms Phylogeny Shared evolutionary important in determining suitability of a model organism Anatomy therefore reflects our long ancestry Studying Development of Humans Rarely use human bein...

Developmental Studies
DEV2011
Julia Young

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