PHY3171 Lecture Notes - Lecture 7: Coronary Artery Disease, Adrenal Medulla, Pheochromocytoma
10 Feb 2019
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Document Summary
Predisposing factors: age, sex, previous illness may create a state of susceptibility. Precipitating factors: exposure to specific noxious disease agents. Reinforcing factors: repeated exposure may aggravate an established disease. Factors positively associated with the risk of development of disease. Not sufficient in their own right to cause a disease. Some associated with several diseases eg. smoking. Some diseases have many risk factors eg. coronary heart disease (chd) More risk factors = more likely to develop disease. For cvd: hypertension, elevated plasma lipid levels, smoking, overweight, diabetes, sedentary life style. Most costly disease for australian health system. Responsible for 11% (. 5 billion) of health expenditure. Emotional costs family + relationship cost. Adrenal cortical diseases - cortical, aldosterone, acth excess. Adrenal medulla - adrenaline, noradrenaline: pheochromocytoma hormone secreting tumour in the adrenal glands. Latrogenic eg. steroid therapy/abuse, sympathomimetic, alcohol abuse, lead/cadmium poisoning, excessive sodium intake.
