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LQB186 (13)

Class Notes for LQB186 at Queensland University of Technology

Human Cell & Molecular Biology

LQB186 Lecture Notes - Lecture 6: Amphiphile, Symbiogenesis, Lipophilicity

Ultrasturcture of Cells Prokaryotic Prokaryotes are organisms whose cells lack a nucleus ('pro' = before ; 'karyon' = nucleus) They belong to the kingdom Monera and have been further clas...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 11: Depolymerization, G0 Phase, Nondisjunction

Cell Division The cell cycle The cell cycle is an ordered set of events which culminates in the division of a cell into two daughter cells It can be roughly divided into two main phases: ...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 12: Apaf1, Cell Membrane, Apoptosis

Cell Death Causes of cell Causes of cell death death Damage to membranes, proteins, mitochondria, lysosomes - By inappropriate enzyme activity, activation of proteins...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 12: Lipid Bilayer, Hydrophile, Cell Membrane

Cell signalling Extracellular The extracellular matrix (ECM) is a mesh of protein fibres and glycoproteins that exist externally of the cell in matrix multicellular organisms ...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 8: Cell Signaling, Methionine, Ubiquitin

Translation Ribosomes In order for translation to occur ribosomes and tRNA are required Ribosomes Ribosomes are made of protein (for stability) and ribosomal RNA (for catalytic activity) Ribosomes provide a structure in w...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture 7: DNA Replication

DNA Replication Watson and Watson and Crick model suggested semiconservative replication Crick model of DNA replication Franklins xray diffraction experiments demonstrated that: the DNA helix is both tightly packed and reg...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 6: Uracil, Deoxyribose, Pentose

Structure of DNA and RNA Nucleic acids Nucleic acids were first discovered in material extracted from the nuclei of cells - Two types of nucleic acid DNA and RNA Nuclei...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 10: Intron, Alternative Splicing, Mature Messenger Rna

Transcription Transcription Transcription is the process by which a DNA sequence (gene) is copied into a complementary RNA sequence by RNA polymerase Free nucleotides exist in the cel...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 1: Point Mutation, Leucine Zipper, Heme

Macromolecule 1 Proteins Proteins and Amino Acids Proteins are comprised of long chains of recurring monomers called amino acids Amino acids all share a common basic structure, with a central carbon atom bound to: An ami...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 2: Lipid Bilayer, Monounsaturated Fat, Exocytosis

Macromolecule 3 Lipids Lipids Lipids are biological molecules characterized by limited solubility in water and solubility in nonpolar organic solvents Lipids are organic molecules basic lipids contain carbon, hydrogen and ...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 5: Endergonic Reaction, Conformational Change, Exergonic Process

Enzymes and metabolic processes Enzymes An enzyme is usually a protein molecule with a characteristic sequence of amino acids that fold to produce a specific threedimensional structure, which gives the molecule unique prop...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 2: Furanose, Aldose, Asymmetric Carbon

Macromolecule 2 Carbohydrates Carbohydrates Carbohydrates organic compounds present in foods and living tissues that are important in many biological processes Carbohydrates are the bodys primary source of energy The pr...

Biomedical Sciences
LQB186
Sally-Anne Stephenson
LQB186 Lecture Notes - Lecture 4: Lipid Bilayer, Turgor Pressure, Osmotic Concentration

Membrane Transport Types of Cellular membranes possess two key qualities: transport 1. They are semipermeable Only certain materials may freely cross large and charged substances are typically blocked 2. They are selectiv...

Biomedical Sciences
LQB186
Sally-Anne Stephenson

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