BABS1201 Lecture Notes - Lecture 3: Olive Oil, Beta Sheet, Glycolipid

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Macromolecules
99% of all living matter is made up of: H C O N (P S)
Inorganic molecules (H2O)
Elements of life in the same ratio
Macromolecule:
A large molecule formed by joining smaller molecules, usually by a dehydration reaction.
Four main classes
Carbohydrates
Lipids
Proteins
Nucleic acids
Macromolecules
Chain-like molecules called polymers
Polymers: consist of many similar or identical subunits joined by covalent bonds (i.e.
monomers)
Synthesis and Breakdown of polymers
Synthesis: a water molecule is lost in "dehydration" to form a new covalent bond
Hydrolysis: breaking down of a polymer, where a water molecule is added to break a
covalent bond
Carbohydrates
Monosaccharides (monomer unit)
o E.g. glucose. CnH2nOn
o Their carbon skeleton ranges from three to seven carbon atoms
o Often drawn with linear carbon skeletons - in water, all monosaccharides with C>3
bend around to form ring structures
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Glucose - major nutrient, central to cellular metabolism.
Broken down for energy in cellular respiration
Used to build many other organic molecules, including amino acids and fatty
acids
Glyceraldehyde
Energy-storing molecule produced by photosynthesis
Two of these from glucose
Galactose - Combines with glucose to form lactose
Fructose - Used to make sucrose
Ribose - RNA and ATP
A modified form is used in building DNA
Disaccharides - two monosaccharides joined by a glycosidic bond
o E.g. Maltose
o
Polysaccharides e.g. starch
Storage Polysacchrides
Starch : stored by plants
o Amylose and amylopectin
o Stored energy can be accessed via hydrolysis
Glycogen: stored by animals in liver and muscle cells.
o Hydrolysis of glycogen releases glucose when the demand for energy increases
(cannot sustain an animal for long periods of time
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Structural polysaccharides
Cellulose
o major component of plant cell walls - used as fibre for humans (we do not have the
enzyme to break down the cellulose)
Chitin (polymer of glucose with N group)
o Found in the exoskeletons of arthropods (insects, spiders, crustaceans, etc)
Amylose < amylopectin < glycogen (least to most branching)
All polymer of glucose
Difference: the number of side chains / branching present
Plant cells
Chloroplast
Starch
Mitochondria
Glycogen granules (lots of branching)
[Carbohydrates - chocolate (sugar, glucose syrup), Jelly (sugar)]
Lipids
Hydrophobic (non-polar); mix poorly with water
Have various forms and functions:
o Energy storage and transport - fats (triclyglycerols or TAGs)
o Structure - phospholipids (cell membranes), sterols
o Chemical messengers - steroids (cholesterol), glycolipids (carbohydrate portions)
o Photoreceptors - carotenoids (makes plants yellow - Vitamin A) photoreceptor -
vitamin A receives red light
Protein that receives light
o Coverings - waxes
How to Make a Fat:
Three fatty acid molecules to one glycerol
Dehydration reaction to form an ester bond
Forms a fat called a triacylglycerol (TAG) or triglyceride
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Document Summary

99% of all living matter is made up of: h c o n (p s) Inorganic molecules (h2o: elements of life in the same ratio. A large molecule formed by joining smaller molecules, usually by a dehydration reaction. Macromolecules: chain-like molecules called polymers, polymers: consist of many similar or identical subunits joined by covalent bonds (i. e. monomers) Synthesis: a water molecule is lost in dehydration to form a new covalent bond: hydrolysis: breaking down of a polymer, where a water molecule is added to break a covalent bond. Starch: chloroplast, mitochondria, glycogen granules (lots of branching) [carbohydrates - chocolate (sugar, glucose syrup), jelly (sugar)] How to make a fat: three fatty acid molecules to one glycerol, dehydration reaction to form an ester bond. Forms a fat called a triacylglycerol (tag) or triglyceride: three fatty acids to glycerol (tricyglycerol) Similar structure of tag phosphate and choline replaces the third fatty acid.

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